Il13-IRES-Cre

모델명

C57BL/6Smoc-Il13em1(IRES-iCre)Smoc

카탈로그

NM-KI-200166

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
IL13

Synonyms

IL-13; P600

NCBI ID

16163

MGI ID

96541

Ensembl ID

ENSMUSG00000020383

Pubmed

IL13

Human Ortholog

IL13

모델 설명

A IRES-iCre expression cassette was knocked into the Il13 gene stop codon site. This gene encodes a multifunctional cytokine. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This cytokine participates in the regulation of immune response, inflammatory response and hematopoietic process.
신청분야：Cre recombinase tool; IL13-expressing cell

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Fig. 1 Cre-mediated recombination in the thymus of Il13Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in  individual cells of the thymus derived from Il13Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Cre-mediated recombination in the spleen of Il13Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in  the spleen derived from Il13Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 3 Detection of tdTomato(red) in various tissues of  Il13Cre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination can be detected in some cells of the thymus and spleen and in individual cells of the stomach and testis. Tdtomato expression can not be observed in the heart. (For more detailed information please contact our technical advisor.)


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