Trpv1-IRES-Cre

모델명

C57BL/6Smoc-Trpv1em1(Myc-IRES-Cre)Smoc

카탈로그

NM-KI-200139

모델 상태

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유전자 요약

Official Symbol
Trpv1

Synonyms

Vr1; VR-1; OTRPC1; TRPV1beta; TRPV1alpha

NCBI ID

193034

MGI ID

1341787

Ensembl ID

ENSMUSG00000005952

Pubmed

Trpv1

Human Ortholog

TRPV1

모델 설명

A Myc-IRES-Cre expression cassette was knocked into the Trpv1 gene stop codon site. Trpv1 is known as transient receptor potential cation channel, subfamily V, member 1. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying the pain caused by heat and capsaicin.
신청분야：Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the brain of Trpv1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the dentate gyrus of Trpv1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Trpv1Cre/+; Rosa26tdTomato/+ mice. Tdtomato is expressed in the brown fat, pancreas, kidney, retina, brain, pituitary gland, heart, lung, liver, stomach, salivary gland and skin. Tdtomato expression can also be observed in individual cells of the testis, epididymis, muscle, spleen, thymus, intestine and colon. (For more detailed information please contact our technical advisor.)


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