Foxj1-EGFP-CreERT2
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C57BL/6Smoc-Foxj1em1(GFP-CreERT2-polyA)Smoc
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NM-KI-200133
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Repository Live
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Foxj1
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Fig.1 CreERT2-mediated recombination in the lung of Foxj1CreERT2/+; Rosa26tdTomato/+ mouse.
TdTomato+ cells (red) were colocalized with GFP+ cells (green) in the bronchial epithelial cells of Foxj1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected in the lung prior to tamoxifen exposure.
Fig.2 CreERT2-mediated recombination in the brain of Foxj1CreERT2/+; Rosa26tdTomato/+ mouse.
TdTomato(red) expression can be detected in the choroid plexus of Foxj1CreERT2/+; Rosa26tdTomato/+ mouse after tamoxifen treatment. Some leakiness were detected in the choroid plexus prior to tamoxifen exposure. EGFP(green) expression can not be observed.
Fig.3 Detection of tdTomato (red) and GFP（green）in various tissues of Foxj1CreERT2/+; Rosa26tdTomato/+ mice. CreERT2 mediated recombination can not be detected in the thymus, heart, lung, stomach, submandibular gland, brown fats, kidney, pancreas, intestine, colon, spleen, ovary, uterus, muscle or skin of female mice(12-13 weeks old). (For more detailed information please contact our technical advisor.)
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On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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