Calb2-IRES-Cre

모델명

C57BL/6Smoc-Calb2em1(IRES-iCre-SV40-pA)Smoc

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NM-KI-200102

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Calb2

모델 설명

A IRES-iCre expression cassette was knocked into the Calb2 gene stop codon site. Calb2 gene encodes calbindin 2. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. The protein plays a key role in the nervous system.
신청분야:Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the pituitary gland of Calb2Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the hippocampus, cortex, olfactory bulb and cerebellar purkinje cells of Calb2Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of  Calb2Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the brain, heart, lung, liver, stomach, kidney, pancreas, intestine, testis, epididymis, spleen, esophagus, thymus and colon.  (For more detailed information please contact our technical advisor.)



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