Slc32a1-IRES-Cre

모델명

C57BL/6Smoc-Slc32a1em1(IRES-iCre)Smoc

카탈로그

NM-KI-200081

모델 상태

Repository Live

PDF 받기

유전자 요약

Official Symbol
Slc32a1

Synonyms

VGAT; Viaat; R75019

NCBI ID

22348

MGI ID

1194488

Ensembl ID

ENSMUSG00000037771

Pubmed

Slc32a1

Human Ortholog

SLC32A1

모델 설명

A IRES-iCre expression cassette was knocked into the Slc32a1 gene stop codon site.
신청분야：Cre recombinase tool; Slc32a1 is a member of the GABA Vesicular Transporter Family. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing cre. This strain may be useful for studying GABaergic neurons function.

검증 데이터

image.png

Fig. 1 Cre-mediated recombination in the brain of Slc32a1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the cortex, hippocampus, hypothalamus and cerebellum of Slc32a1Cre/+; Rosa26tdTomato/+ mouse.

image.png

Fig. 2 Detection of tdTomato(red) in various tissues of Slc32a1Cre/+; Rosa26tdTomato/+ mice. Cre mediated recombination can be detected in the cortex, hippocampus, hypothalamus, cerebellum, retinal ganglion cell layer, retinal outer plexiform layer and inner nuclear layer. TdTomato can also be detected in individual cells of the sailvary gland, kidney, pancreas, large intestine, spleen, thymus, testis and epididymis. Tdtomato expression can not be observed in the heart, lung, liver, small intestine and skin. (For more detailed information please contact our technical advisor.)


당신은 또한 좋아할 수 있습니다

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

조회
Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!

At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.

조회