Gad2-IRES-Cre

모델명

C57BL/6Smoc-Gad2em1(IRES-iCre-pA)Smoc

카탈로그

NM-KI-200078

모델 상태

Repository Live

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유전자 요약

Official Symbol
Gad2

Synonyms

GAD65; Gad-2; GAD(65); 6330404F12Rik

NCBI ID

14417

MGI ID

95634

Ensembl ID

ENSMUSG00000026787

Pubmed

Gad2

Human Ortholog

GAD2

모델 설명

A IRES-iCre-pA expression cassette was knocked into the Gad2 gene stop codon site.
신청분야：By mating the reporter mice with Cre-expressing mice, Gad2 positive cells derived from double-positive mice were permanently labeled by fluorescent protein. It can be used to trace Gad2-positive cells.

검증 데이터

Gad2-iCre-1.png

Fig. 1 Detection of tdTomato (red) in the retina of Gad2icre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination in the retinal ganglion cell layer (yellow arrow) and inner nuclear layer (red arrow) of Gad2iCre/+; Rosa26tdTomato/+ mouse. 

Gad2-iCre-2.png

Fig. 2 Detection of tdTomato (red) in some cells of the cortex and hippocampus drived from Gad2icre/+; Rosa26tdTomato/+ mice.

Gad2-iCre-3.png

Fig. 3 Detection of tdTomato (red) in various tissues of Gad2icre/+; Rosa26tdTomato/+ mice. Cre-mediated recombination in some cells of the brain, pituitary gland, retina, lung, heart, liver, submandibular gland, brown fat, kidney, pancreas, intestine, colon,  epididymis, muscle, skin and thymus can be observed. Tdtomato can not be detected in the spleen and testis. (For more detailed information please contact our technical advisor.)

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