Mnx1-IRES-Cre

모델명

C57BL/6Smoc-Mnx1em1(IRES-Cre-WPRE-polyA)Smoc

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NM-KI-200010

모델 상태

Embryo cryopreservation

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유전자 요약

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Mnx1

모델 설명

A IRES-Cre-WPRE-polyA expression cassette was knocked into the Mnx1 gene stop codon site. When crossed with a strain carrying a gene flanked by loxP sites, the flanked gene will be removed in cells expressing Mnx1. These mice may be useful for studying spinal muscular atrophy (SMA).
신청분야:Cre recombinase tool

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Fig. 1 Cre-mediated recombination in the spinal cord of Mnx1Cre/+; Rosa26tdTomato/+ mouse. TdTomato(red) expression can be detected in the spinal cord of Mnx1Cre/+; Rosa26tdTomato/+ mouse.

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Fig. 2 Detection of tdTomato(red) in various tissues of Mnx1Cre/+; Rosa26tdTomato/+ mice. Tdtomato expression can be detected in the brain, kidney, intestine, colon, eyes, ovary, salivary gland, stomach, liver, skin, heart, lung, pituitary gland, muscle, spleen, brown fat and thymus. (For more detailed information please contact our technical advisor.)



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