Cdh1-2A-DreERT2

모델명

C57BL/6Smoc-Cdh1em3(2A-DreERT2)Smoc

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NM-KI-190031

모델 상태

Sperm cryopreservation

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유전자 요약

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Cdh1

모델 설명

A 2A-DreERT2 expression cassette was knocked into the Cdh1 gene stop codon site via CRISPR/Cas mediated recombination.
신청분야:Dre recombinase tool

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Fig. 1 DreERT2-mediated recombination in the liver of Cdh1DreERT2/+;R26tdtomato/+ mouse. Tdtomato (red) expression can be detected in the liver after tamoxifen treatment. Cdh1 gene encodes E-cadherin(E-CAD), a calcium-dependent adhesion  molecule that expressed primarily in epithelial cells. (Documented in the following reference.)




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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

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