Cdkn2a-Luc-2A-tdTomato-2A-CreERT2(p16-Luc-2A-tdTomato-2A-CreERT2)

모델명

C57BL/6Smoc-Cdkn2aem(Luc-tdTomato-CreERT2)Smoc

카탈로그

NM-KI-18039

모델 상태

Repository Live

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유전자 요약

Official Symbol
Cdkn2a

Synonyms

Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a)

NCBI ID

12578

MGI ID

104738

Ensembl ID

ENSMUSG00000044303

Pubmed

Cdkn2a

Human Ortholog

CDKN2A

모델 설명

A Luc-2A-tdTomato-2A-CreERT2-WPRE-pA cassette was fused in-frame with exon2 of p16INK4a transcript such that the exogenous proteins would be translated followed by the first 62aa of Cdkn2a.

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Cdkn2a-2.png

Fig1  Luciferase reporter assays in MEF cells(WT and Cdkn2a KI MEFs).

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