Dbh-IRES-Cre

모델명

C57BL/6Smoc-Dbhem1(IRES-Cre)Smoc

카탈로그

NM-KI-232144

모델 상태

Sperm cryopreservation

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유전자 요약

Official Symbol
Dbh

Synonyms

-

NCBI ID

13166

MGI ID

94864

Ensembl ID

ENSMUSG00000000889

Pubmed

Dbh

Human Ortholog

DBH

모델 설명

The IRES-Cre expression cassette was knocked into the Dbh gene stop codon site.

검증 데이터

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Fig1. Cre mediated recombination in brain of DbhCre/+;Rosa26tdTomato/+ mouse. 

Abbr: LC:Locus Coeruleus

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Fig2. Cre mediated recombination in adrenal glands of DbhCre/+;Rosa26tdTomato/+ mouse.

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Fig3. Detection of tdTomato(red) in various tissues of DbhCre/+;Rosa26tdTomato/+ mouse. Expression tissues include: brain, adrenal glands, retina, heart, lungs, salivary glands, spinal cord, kidneys, colon, small intestine, spleen, testicles and epididymis, muscles, skin, thymus, pituitary gland. A few cells expressed in liver, stomach, brown fat, pancreas.(5.5-months old, male) (For more detailed information please contact our technical advisor.)

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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

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