hAGT/hREN(2)
모델명
C57BL/6JSmo-Agttm1(hAGT)Ren1tm1(hREN)Smoc
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NM-HU-234349
모델 상태
Repository Live
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Fig.1 Detection of AGT(A) and REN(B) expression in liver by RT-PCR.
Wild type: only one band at 232 bp with primers F1/R1(mAgt); only one band at 235 bp with primers F3/R4(mRen);
Homozygous: only one band at 360 bp with primers F2/R2(hAGT); only one band at 202 bp with primers F4/R4(hREN)
Abbr. M, DNA marker; HO, homozygous; WT, wild type.

Fig.2 Detection of hAGT and mAGT expression in plasma by ELISA (male, n=3, 7-8wks).
Abbr. HO, homozygous; WT, wild type.

Fig.3 Detection of hREN expression in plasma by ELISA (male, n=3, 7-8wks).
Abbr. HO, homozygous; WT, wild type.

Fig.4 Detection of mANG2 expression in plasma by ELISA (male, n=3, 7-8wks).
Abbr. HO, homozygous; WT, wild type.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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