Rag2-KO/hHER2

모델명

C57BL/6JSmo-Rag2em2Erbb2tm1(hHER2)Smoc

카탈로그

NM-HU-234873

모델 상태

Embryo cryopreservation

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유전자 요약

Gene Symbol
Erbb2

모델 설명

The hHER2(NM-HU-200115) was crossed with Rag2-KO(NM-KO-190429) to generate Rag2-KO/hHER2 mice.

검증 데이터

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Fig.1 Subcutaneous xenograft tumor growth of NCI-N87 in Rag2-KO/hHER2 mouse model. 

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Fig 2. Body weight change and means of body weight of Rag2-KO/hHER2 mouse model after tumor inoculation. 

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Fig.3 In vivo efficacy of Disitamab Vedotin on Rag2-KO/hHER2 mice bearing NCI-N87 tumor (n=2-6, female, 6-8 weeks old).


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