hASGR1
모델명
C57BL/6JSmo-Asgr1tm(hASGR1)Smoc
카탈로그
NM-HU-230065
모델 상태
Repository Live
유전자 요약
Gene Symbol
Asgr1
모델 설명
검증 데이터
Fig.1 Detection of ASGR1 expression in liver by RT-PCR.
Wild type: only one band at 224 bp with primers F1/R1(mAsgr1);
Homozygous: only one band at 326 bp with primers F2/R2(hASGR1).
Abbr. M, DNA marker; HO, homozygous; WT, wild type.
Fig.2 Detection of human ASGR1 expression in hASGR1 mice by WB.
Abbr. M, marker; WT, wild type; HO, Homozygous; NC, negetive control, blank.
Fig.3 Body weight and ratios of liver to body weight of hASGR1 knockin mice. (n=4-5, 7-8-week-old, Mean±SEM, Unpaired t-test, ns: no significant)
Abbr. HO, homozygous; WT, wild type.
Table 1. Biochemical test of serum from hASGR1 knockin mice. Values are expressed as mean±SEM.
Abbr. HO, homozygous; WT, wild type.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회Customizing Mouse Models: Delivering in 100 Days to Speed Up Your Research!
At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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