hCD3EDG/hCD19
모델명
C57BL/6JSmo-Cd3etm1(hCD3E)Cd3dtm1(hCD3D)Cd3gtm1(hCD3G)Cd19tm1(hCD19)Smoc
카탈로그
NM-HU-220109
모델 상태
Repository Live
모델 설명
검증 데이터
Fig.1 Detection of immune phenotype in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.
Fig.2 Detection of phenotype in Peripheral blood in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.
Fig.3 Detection of phenotype in Spleen in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.
Fig.4 Detection of phenotype in Lymph node in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice.
Fig.5 Detection of CD3 and CD19 expression in Blood in hCD3EDG/hCD19 dKI and WT mice
Fig.6 The Body weight of HO/HO hCD3EDG/hCD19 mice.
Fig.7 Detection of mIgG (A) and mIgM (B) expression in serum in WT C57BL/6 and HO/HO hCD3EDG/hCD19 mice by ELISA. (n=6)
Abbr. WT, wild type.
Fig.8 Detection of immune phenotype in peripheral blood in HO/HO hCD3EDG/hCD19 mice.
Fig.9 The weight of different tissues in HO/HO hCD3EDG/hCD19 mice.
Table.1 Blood routine examination in hCD3EDG/hCD19 dKI mice (n=6 /group).
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.
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