hIL3/hCSF2

모델명

C57BL/6JSmo-Il3tm3(hIL3)Csf2tm3(hCSF2)/Smoc

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NM-HU-190065

모델 상태

Embryo cryopreservation

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모델 설명

The endogenous mouse Il3 and Csf2 gene was replaced by human IL3 and CSF2 gene.
신청분야:Immunotherapy,cancer research,drug screening

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image.png

Fig.1 Detection of mCSF2(A) and hCSF2(B) expression in serum by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected

Note.hIL3/hCSF2 and C57BL/6 mice were i.p. injected with LPS for 2h.

image.png

Fig.2 Detection of mIL3(A) and hIL3(B) expression in splenocyte by ELISA(n=3). 

Abbr. HO, homozygous; WT, wild type; N.D. not detected.

Note. Splenocyte were stimulated with ConA and IL2 in vitro for 48h.



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