hCD19
모델명
C57BL/6JSmo-Cd19tm1(hCD19) Smoc
카탈로그
NM-HU-00110
모델 상태
Repository Live
유전자 요약
Gene Symbol
CD19
모델 설명
검증 데이터
Fig.1 Expression characterization of hCD19 on B cells in blood in hCD19 knockin mice.
Fig.2 Expression characterization of hCD19 on B cells in spleen in hCD19 knockin mice.
Fig.3 Expression characterization of hCD19 on B cells in thymus in hCD19 knockin mice.
Fig.4 Body weight and ratios of spleen, thymus and MLN to body weight of 8-week-old hCD19 knockin mice. (n=6 for all groups, Mean±SEM, Unpaired t-test, *P<0.05, **P<0.01).
Abbr. HO, homozygous; WT, wild type; MLN, mesenteric lymph nodes.
Table 1. Blood routine examination of hCD19 knockin mice. Values are expressed as mean±SEM.
Abbr. HO, homozygous; WT, wild type.
Table 2. Biochemical test of serum from hCD19 knockin mice. Values are expressed as mean±SEM.
Abbr. HO, homozygous; WT, wild type.
Fig.5 Blood biochemical detection of 8-week-old hCD19 knockin mice. (n=6 for all groups, Mean±SEM).
Abbr. HO, homozygous; WT, wild type.
Fig.6 Detection of myeloid cell subsets in the blood of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).
Abbr. WT, wild type; HO, homozygous.
Fig.7 Detection of lymphocyte subsets in the blood of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).
Abbr. WT, wild type; HO, homozygous.
Fig.8 Detection of myeloid cell subsets in the spleen of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).
Abbr. WT, wild type; HO, homozygous.
Fig.9 Detection of lymphocyte subsets in the spleen of 8-week-old hCD19 knockin mice by FACS (n=3 in all groups).
Abbr. WT, wild type; HO, homozygous.
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Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
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At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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