Ifng-Venus-Luc
모델명
C57BL/6Smoc-Ifngem1(IRES-Venus-Luci)Smoc
카탈로그
NM-KI-18041
모델 상태
Embryo cryopreservation
유전자 요약
Official Symbol
Ifng
모델 설명
검증 데이터
Fig1.MC38-OVA tumor volumes in Ifng-Venus-Luci reporter mice treated or not with anti-PD-1 mAb. Arrows indicate treatment days.
Fig2. In vivo imaging validation of MC38-OVA tumors in Ifng-Venus-Luci reporter mice treated or not with anti-PD-1 mAb.
In PBS treated control tumor, the IFNγ signal increased as the tumor growing. In anti-PD1 treated tumor, increased average BLI (Bioluminescent imaging) of IFNγ was shown 48h post the first dose compared to control group; as the tumor regression upon PD1 treatment, the IFNγ signal in tumor decreased as well.
The data is provided by Crownbio.
당신은 또한 좋아할 수 있습니다
On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.
조회At GenoBioTX, we understand that the lengthy wait times for gene-modified mouse models can hinder your research progress. Traditional methods often require 6-9 months, leading to delays and increased costs. That’s why we’re thrilled to introduce our innovative service designed to streamline this process and deliver results faster.
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