Npy1r-KO

모델명

C57BL/6Smoc-Npy1Rem1Smoc

카탈로그

NM-KO-190999

모델 상태

Embryo cryopreservation

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유전자 요약

Official Symbol
Npy1r

Synonyms

Npyr， Y1-R， NPY1-R

NCBI ID

18166

MGI ID

104963

Ensembl ID

ENSMUSG00000036437

Pubmed

Npy1r

Human Ortholog

NPY1R

모델 설명

Exon 2 of Npy1r gene was deleted to generate Npy1r knockout mice.
신청분야：Endocrine and metabolic, obesity, hyperinsulinemia; nervous system, pain

Disease Connection

Obesity

Phenotype(s)

MGI:3639781

Reference(s)

Raposinho PD, Pedrazzini T, White RB, Palmiter RD, Aubert ML, Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. Endocrinology. 2004 Jan;145(1):304-10

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